Tizanidine Information
Pronunciation
tye ZAN i deen
What is this drug used for?
• It is used to relax muscles.
• It may be given to you for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
• Dry mouth
• Fatigue
• Loss of strength and energy
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
• Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.
• Urinary tract infection like blood in the urine, burning or painful urination, passing a lot of urine, fever, lower abdominal pain, or pelvic pain.
• Severe dizziness
• Passing out
• Confusion
• Sensing things that seem real but are not
• Mood changes
• Behavioral changes
• Slow heartbeat
• Chills
• Sore throat
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
TiZANidine may be confused with nizatidine, tiaGABine.
Zanaflex may be confused with Xiaflex.
Storage and Stability
Store at 25°C (77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F)
Adverse Reactions
Cardiovascular: Bradycardia, hypotension
Central nervous system: Delusion, dizziness, drowsiness, drug withdrawal, nervousness, sedated state, speech disturbance, visual hallucination
Gastrointestinal: Constipation, vomiting, xerostomia
Genitourinary: Urinary frequency, urinary tract infection
Hepatic: Abnormal hepatic function tests
Hypersensitivity: Hypersensitivity reaction
Infection: Infection
Neuromuscular & skeletal: Asthenia, dyskinesia
Ophthalmic: Blurred vision
Respiratory: Flu-like symptoms, pharyngitis, rhinitis
Rare but important or life-threatening: Anaphylaxis, arthralgia, depression, exfoliative dermatitis, fatigue, hepatitis, hepatotoxicity, muscle spasm, paresthesia, seizure, skin rash, Stevens-Johnson syndrome, syncope, tremor, ventricular tachycardia
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