Bupropion Information
Pronunciation
(byoo PROE pee on)
What is this drug used for?
• It is used to treat low mood (depression).
• It is used to treat seasonal affective disorder (SAD).
• It is used to help you stop smoking.
• It may be given to you for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
• Abdominal pain
• Tremors
• Anxiety
• Nightmares
• Nausea
• Vomiting
• Constipation
• Diarrhea
• Passing gas
• Dry mouth
• Trouble sleeping
• Nose irritation
• Throat irritation
• Sweating a lot
• Lack of appetite
• Tablet shell in stool
• Weight gain or loss
• Joint pain
• Muscle pain
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
• Depression like thoughts of suicide, anxiety, agitation, irritability, panic attacks, mood changes, behavioral changes, or confusion
• Confusion
• Behavioral changes
• Seizures
• Thoughts of homicide
• Forceful actions
• Anger
• Sensing things that seem real but are not
• Severe headache
• Severe dizziness
• Passing out
• Chest pain
• Fast heartbeat
• Abnormal heartbeat
• Swelling
• Shortness of breath
• Hearing changes
• Noise or ringing in the ears
• Passing a lot of urine
• Swollen glands
• Trouble moving
• Trouble focusing
• Vision changes
• Eye pain
• Eye irritation
• Eye redness
• Eye swelling
• Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
Aplenzin may be confused with Albenza, Relenza
BuPROPion may be confused with busPIRone
Forfivo XL may be confused with Forteo
Wellbutrin XL may be confused with Wellbutrin SR
Zyban may be confused with Diovan
Storage and Stability
Store at 15°C to 30°C (59°F to 86°F). Protect from light and moisture.
Adverse Reactions
Cardiovascular: Cardiac arrhythmia, chest pain, flushing, hypertension (may be severe), hypotension, palpitations, tachycardia
Central nervous system: Abnormal dreams, abnormal sensory symptoms, abnormality in thinking, agitation, akathisia, anxiety, central nervous system stimulation, confusion, depression, dizziness, drowsiness, dystonia, headache, hostility, insomnia, irritability, lack of concentration, memory impairment, migraine, nervousness, pain, paresthesia, sleep disorder, twitching
Dermatologic: Diaphoresis, pruritus, skin rash, urticaria, xeroderma
Endocrine & metabolic: Decreased libido, hot flash, menstrual disease, weight gain, weight loss
Gastrointestinal: Abdominal pain, anorexia, constipation, diarrhea, dysgeusia, dyspepsia, dysphagia, flatulence, increased appetite, nausea, oral mucosa ulcer, vomiting, xerostomia
Genitourinary: Urinary frequency, urinary tract infection, urinary urgency, vaginal hemorrhage
Hypersensitivity: Hypersensitivity reaction
Infection: Infection
Neuromuscular & skeletal: Arthralgia, arthritis, asthenia, dyskinesia, myalgia, neck pain, tremor
Ophthalmic: Blurred vision, diplopia
Otic: Auditory disturbance, tinnitus
Renal: Polyuria
Respiratory: Bronchitis, cough, epistaxis, increased cough, nasopharyngitis, pharyngitis, rhinitis, sinusitis, upper respiratory infection
Miscellaneous: Accidental injury, fever
Rare but important or life-threatening: Abnormal stools, accommodation disturbance, acute myocardial infarction, aggressive behavior, akinesia, alopecia, amnesia, anaphylactic shock, anaphylaxis, anemia, angioedema, angle-closure glaucoma, aphasia, ataxia, atrioventricular block, bronchospasm, bruxism, cerebrovascular accident, change in prothrombin time, chills, colitis, coma, complete atrioventricular block, cutaneous lupus erythematosus (Hannah 2018), cystitis, deafness, delirium, delusion, depersonalization, derealization, drug-induced Parkinson disease, dry eye syndrome, dysarthria, dyspareunia, dysphoria, dysuria, ecchymoses, edema, EEG pattern changes, ejaculatory disorder, emotional lability, erythema multiforme, esophagitis, euphoria, exfoliative dermatitis, extrapyramidal reaction, extrasystoles, facial edema, gastric ulcer, gastroesophageal reflux disease, gastrointestinal hemorrhage, gingival hemorrhage, gingivitis, glossitis, glycosuria, gynecomastia, hallucination, hepatic injury, hepatic insufficiency, hepatitis, hirsutism, homicidal ideation, hyperglycemia, hyperkinetic muscle activity, hypertonia, hypoesthesia, hypoglycemia, hypokinesia, hypomania, hyponatremia, impotence, increased intraocular pressure, increased libido, increased thirst, inguinal hernia, intestinal perforation, jaundice, leukocytosis, leukopenia, lower limb cramp, lymphadenopathy, maculopapular rash, malaise, manic behavior, menopause, muscle rigidity, musculoskeletal chest pain, myasthenia, mydriasis, myoclonus, neuralgia, neuropathy, nonimmune anaphylaxis, orthostatic hypotension, painful erection, pancreatitis, pancytopenia, panic, paranoid ideation, peripheral edema, phlebitis, pneumonia, prostatic disease, psychiatric signs and symptoms, psychosis, pulmonary embolism, restlessness, rhabdomyolysis, salpingitis, sciatica, seizure (dose-related), serum sickness-like reaction, SIADH, sialorrhea, skin photosensitivity, Stevens-Johnson syndrome, stomatitis, subacute cutaneous lupus erythematosus (Hannah 2018), suicidal ideation, syncope, tardive dyskinesia, thrombocytopenia, tongue edema, type IV hypersensitivity reaction, urinary incontinence, urinary retention, vaginitis, vasodilation, vertigo –
