Glenvirax Tablet- 400mg

Manufactured by Glenmark Pharmaceuticals Ltd

Composition: Aciclovir

Prescription Required: Yes

Glenvirax Tablet is an antiviral agent which is used in the treatment of infections caused by herpes virus such as chickenpox and herpes zoster. The effect of this medicine is higher if it is started as soon as symptoms appear.

Side Effects

• Swelling and redness at the injection siteSEVERE
• Abdominal painSEVERE
• Increased thirstSEVERE
• Loss of appetiteSEVERE
• Unusual tiredness and weaknessSEVERE
• Black or tarry stoolsSEVERERARE
• Fever with chillsSEVERERARE
• SeizuresSEVERERARE
• Unusual bleedingSEVERERARE
• Diarrhea
• Headache

SEVERE

Contact your doctor immediately if any of these symptoms are experienced on a regular basis.

RARE

Observed in a small fraction of population.

This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Commonly asked questions for Glenvirax Tablet

Onset of action

The peak effect of this medicine can be observed in 1.5 to 2 hours after an oral dose and 2 hours after an intravenous dose.

Duration of effect

The effect of this medicine lasts for an average duration of 9 to 12 hours.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit tendencies have been reported.

Pregnancy warnings

This medicine is recommended for pregnant women. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine.

Breast-feeding warnings

This medicine is excreted through the breastmilk. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of any undesired effects is necessary.

Uses of Glenvirax Tablet

• Herpes Zoster Infections

Glenvirax Tablet is used in the treatment of herpes zoster infection which is a viral infection caused by varicella-zoster virus.

• Genital Herpes

Glenvirax Tablet is used in the treatment of genital herpes which is a sexually transmitted viral infection caused by herpes simplex virus.

• Chickenpox

Glenvirax Tablet is used in the treatment of chicken pox which is a viral infection caused by varicella-zoster virus.

Contraindications for Glenvirax Tablet

• Allergy

If you have a known allergy to Glenvirax Tablet or any other medicine belongs to the class anti-herpes virals.

Dosage

Missed / Overdose instructions

·       Missed Dose

·       Overdose

Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Interactions

Whenever you take more than one medicine, or mix it with certain foods or beverages, you’re at risk of a drug interaction.

Interaction with Alcohol

·       Alcohol

– Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

• Phenytoin

MODERATE

• Tacrolimus

MAJOR

• Sulfasalazine

MODERATE

Other Interactions

·       Disease

·       Food

·       Lab Test

• Impaired kidney function

MAJOR

Glenvirax Tablet should be used with caution in the patients with the pre-existing kidney injury. Inform the doctor if you experience any symptoms of sudden weight gain, changes in the frequency of urination. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

• Neurological disorder

MODERATE

Use of high-dose intravenous Glenvirax Tablet may increase the risk of neurotoxicity, especially in the elderly population with a neurological disorder, kidney or liver injury. Inform the doctor if you experience any symptoms of tremors, confusion, and seizures. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

This is not an exhaustive list of interactions. Always inform your doctor beforehand about your medical history and current medications.

Instructions

General instructions

Take Glenvirax Tablet with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor. Drink adequate amount of water in order to reduce the risk of kidney injury.

Warnings

Warnings for special population

·       Pregnancy warnings

–

This medicine is recommended for pregnant women. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine.

·       Breast-feeding warnings

–

This medicine is excreted through the breastmilk. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of any undesired effects is necessary.

General warnings

·       Hydration

–

Glenvirax Tablet may increase the risk of kidney injury when taken with other medicines that cause kidney injury. Adequate water should be consumed to prevent the accumulation of the medicine.

·       Impaired kidney function

–

Glenvirax Tablet is used with caution in the patients with the severe kidney injury. Suitable dose adjustments are to be made based on the clinical condition.

·       Elderly population

–

Glenvirax Tablet is used with caution in the elderly population with kidney injury or liver injury due to increase in the risk of neurological problems. Dose adjustments are to be made based on the clinical condition.

·       Pediatric population

–

The safety and efficacy of the oral formulation of Glenvirax Tablet has not been established in children less than 2 years of age. –