Molnupiravir (Movfor) 200 mg – 40 Tablets

$84.75

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Molnupiravir (Movfor) 200 mg – 40 Tablets
$84.75

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Molnupiravir Information

What is the purpose of this drug?

It is used to treat COVID-19 in SARS-CoV-2 patients.

 

Negative Effects

 

1-10%

diarrhea (2 percent)

Nausea (1%)

Dizziness (1%)

≤2%

Selected anomalies in Grades 3 and 4 laboratory chemistry (ALT, AST, creatinine, and lipase) and hematology (hemoglobin, platelets, and leukocytes)

 

Cautions

 

There are little accessible clinical data; significant and unanticipated side effects may occur but have not yet been recorded.

When supplied to pregnant women, this substance may be teratogenic.

 

Toxicological effects on bone and cartilage

 

Not approved for use in individuals less than 18 years due to potential effects on bone and cartilage development

On repeated dosage, bone and cartilage damage was reported in rats.

Safety and effectiveness in pediatric patients have not been demonstrated.

 

Pregnancy

 

Contraindicated during pregnancy

 

Dosage Modifications

 

Renal impairment

 

Mild or moderate (eGFR >30 mL/min): No dose modification is required.

Patients with severe (eGFR 30 mL/min), end-stage renal disease, or dialysis: Not investigated for pharmacokinetics; not anticipated to have a major impact on NHC (N4-hydroxycytidine) exposure.

 

hepatic dysfunction

 

Mild to severe (Child-Pugh Classes A to C): No dose modification is necessary.

Hepatic elimination is not likely to be a key route of NHC clearance, according to preclinical evidence.

 

Considerations for Dosage

 

Prior to commencing treatment, the pregnancy status of women of reproductive potential should be determined.

 

Restrictions on usage

 

Not approved for use in patients younger than 18

Not permitted for use in individuals who require hospitalization because to COVID-19

Not permitted for usage for more than five consecutive days

Not permitted for preexposure or postexposure prophylaxis against COVID-19.

 

Administration

 

Administration by Mouth

 

Oral administration, with or without food

 

Missed dose

 

<10 hours: Take the missing dosage as soon as possible and resume your regular dosing routine.

>10 hours: Skip the dosage and take the following one at the normal time.

Do not duplicate the dose to compensate for a missing one.

 

Storage

 

Temperature variations between 15 and 30 degrees Celsius (59 and 86 degrees Fahrenheit) are acceptable.