What is this drug used for?
• It is used to lower uric acid in the blood.
• It is used to prevent high uric acid levels during chemo.
• It may be given to you for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
• Diarrhea
• Nausea
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
• Kidney problems like unable to pass urine, blood in the urine, change in amount of urine passed, or weight gain.
• Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.
• Infection
• Kidney stone like back pain, abdominal pain, or blood in the urine.
• Painful urination
• Eye irritation
• Vision changes
• Joint pain
• Swollen glands
• Shortness of breath
• Excessive weight gain
• Swelling of arms or legs
• Chest pain
• Bruising
• Bleeding
• Severe loss of strength and energy
• Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes.
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.
Medication Safety Issues
Sound-alike/look-alike issues:
Allopurinol may be confused with ApresolineZyloprim may be confused with zolpidem, ZORprin, Zovirax
Storage and Stability
Powder for injection: Store at 20°C to 25°C (68°F to 77°F). Following preparation, intravenous solutions in NS or D5W should be stored at 20°C to 25°C (68°F to 77°F). Do not refrigerate reconstituted and/or diluted product. Must be administered within 10 hours of solution preparation.
Tablet: Store at 15°C to 25°C (59°F to 77°F). Store in a dry place. Protect from light.
Adverse Reactions
1% to 10%:
Dermatologic: Maculopapular rash (≤3%; pruritic), skin rash (≤2%)
Endocrine & metabolic: Gout (≤6%; acute)
Gastrointestinal: Nausea (1%), vomiting (≤1%)
Renal: Renal failure syndrome (≤1%), renal insufficiency (≤1%)
Frequency not defined:
Gastrointestinal: Diarrhea
Hepatic: Increased serum alanine aminotransferase, increased serum alkaline phosphatase, increased serum aspartate aminotransferase
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